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The American Society of Clinical Oncology (ASCO) first published evidence-based clinical practice guidelines for the use of tumor markers in breast cancer in 1996. ASCO guidelines are updated at intervals by an Update Committee of the original Expert Panel. The last update of the tumor markers guideline was published in 2000. For the 2007 update, the Panel expanded the scope of the guideline to include a broader range of markers in breast cancer.

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